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Implanted System for Orthostatic Hypotension in Multiple-System Atrophy
06 Apr 2022
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Research
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#neuroimaging
#epidural electrical stimulation
I am delighted to share our work published in the New England Journal of Medicine:
Implanted System for Orthostatic Hypotension in Multiple-System Atrophy
New England Journal of Medicine, Vol. 386, No. 14, pp. 1339–1344 (April 2022)
Jordan W. Squair, Maxime Berney, Mayte Castro Jimenez, Nicolas Hankov, Robin Demesmaeker, Suje Amir, Aurélie Paley, Sergio Hernandez-Charpak, Gregory Dumont, Léonie Asboth, Gilles Allenbach, Fabio Becce, Patrick Schoettker, Grégoire Wuerzner, Julien F. Bally, Grégoire Courtine, Jocelyne Bloch
In this work, I led the guidance of the EES neuroprosthetic implantation over the lower thoracic spinal levels (T10–T12) of an individual heavily suffering from orthostatic hypotension due to Multiple System Atrophy (MSA). The guidance was based on personalized anatomical models built from high-resolution MR and CT structural imaging. The successful implantation and stimulation restored sufficient hemodynamic regulation to enable the participant to stand and walk despite more than a year of immobility.
Sergio Daniel Hernandez Charpak is a PhD Computational Scientist, a Physicist and Computing Engineer researching in the interface between AI / medical imaging in healthcare, and also an enthousiast of travel, hiking, chess and piano.